Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Kdr  kinase insert domain protein receptor   (Synonyms: Flk1, Flk-1, orv, vascular endothelial growth factor receptor- 2, VEGFR2, VEGFR-2, VEGF receptor-2)
Results	Reference
1	J:174608 Chong DC, Koo Y, Xu K, Fu S, Cleaver O, Stepwise arteriovenous fate acquisition during mammalian vasculogenesis. Dev Dyn. 2011 Sep;240(9):2153-65
1	J:177484 Daane JM, Downs KM, Hedgehog signaling in the posterior region of the mouse gastrula suggests manifold roles in the fetal-umbilical connection and posterior morphogenesis. Dev Dyn. 2011 Sep;240(9):2175-93
1*	J:247900 Downs KM, Systematic localization of Oct-3/4 to the gastrulating mouse conceptus suggests manifold roles in mammalian development. Dev Dyn. 2008 Feb;237(2):464-75
1	J:86673 Duan LJ, Nagy A, Fong GH, Gastrulation and angiogenesis, not endothelial specification, is sensitive to partial deficiency in vascular endothelial growth factor-a in mice. Biol Reprod. 2003 Dec;69(6):1852-8
1	J:109435 Ema M, Takahashi S, Rossant J, Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors. Blood. 2006 Jan 1;107(1):111-7
1	J:296645 Hamline MY, Corcoran CM, Wamstad JA, Miletich I, Feng J, Lohr JL, Hemberger M, Sharpe PT, Gearhart MD, Bardwell VJ, OFCD syndrome and extraembryonic defects are revealed by conditional mutation of the Polycomb-group repressive complex 1.1 (PRC1.1) gene BCOR. Dev Biol. 2020 Jul 18;
1*	J:306370 Harland LTG, Simon CS, Senft AD, Costello I, Greder L, Imaz-Rosshandler I, Gottgens B, Marioni JC, Bikoff EK, Porcher C, de Bruijn MFTR, Robertson EJ, The T-box transcription factor Eomesodermin governs haemogenic competence of yolk sac mesodermal progenitors. Nat Cell Biol. 2021 Jan;23(1):61-74
1*	J:119027 Inman KE, Downs KM, Brachyury is required for elongation and vasculogenesis in the murine allantois. Development. 2006 Aug;133(15):2947-59
1	J:178675 Ishitobi H, Wakamatsu A, Liu F, Azami T, Hamada M, Matsumoto K, Kataoka H, Kobayashi M, Choi K, Nishikawa S, Takahashi S, Ema M, Molecular basis for Flk1 expression in hemato-cardiovascular progenitors in the mouse. Development. 2011 Dec;138(24):5357-68
1*	J:242135 Rodriguez AM, Jin DX, Wolfe AD, Mikedis MM, Wierenga L, Hashmi MP, Viebahn C, Downs KM, Brachyury drives formation of a distinct vascular branchpoint critical for fetal-placental arterial union in the mouse gastrula. Dev Biol. 2017 May 15;425(2):208-222
1	J:96124 Sakurai Y, Ohgimoto K, Kataoka Y, Yoshida N, Shibuya M, Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice. Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1076-81
1*	J:26846 Shalaby F, Rossant J, Yamaguchi TP, Gertsenstein M, Wu XF, Breitman ML, Schuh AC, Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature. 1995 Jul 6;376(6535):62-6
1*	J:151374 Teichert AM, Scott JA, Robb GB, Zhou YQ, Zhu SN, Lem M, Keightley A, Steer BM, Schuh AC, Adamson SL, Cybulsky MI, Marsden PA, Endothelial nitric oxide synthase gene expression during murine embryogenesis: commencement of expression in the embryo occurs with the establishment of a unidirectional circulatory system. Circ Res. 2008 Jul 3;103(1):24-33
1	J:174152 Xu K, Sacharidou A, Fu S, Chong DC, Skaug B, Chen ZJ, Davis GE, Cleaver O, Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling. Dev Cell. 2011 Apr 19;20(4):526-39